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华东师范大学应用心理学导师介绍:冯国平

发布时间: 2023-01-17 09:50:02


冯国平博士:浙江医科大学本科毕业,上海第二医科大学硕士、纽约州大学博士、华盛顿大学-圣路易博士后;曾任美国杜克大学神经生物学系助理教授,终身副教授;现任麻省理工学院大脑与认知科学系McGovern大脑研究所Poitras教授,兼职华东师范大学特聘(国家千人计划引进)教授。研究方向:研究神经突触和环路功能及精神疾病发生机理,创建神经系统研究新技术。
►Research directions:
(1) Dissect synaptic and circuitry mechanisms of abnormal behaviors in psychiatric disorders; (2) Develop cutting-edge genetic tools for studying synaptic and circuitry function and dysfunction.
►代表性论文:
1.Feng,G.,Deak,P.,Chopra,M. and Hall,L.M. (1995) Cloning and functional analysis of tipE: A novel membrane protein which enhances Drosophila para sodium channel function. Cell 82:1001-1011.
2.Feng*,G.,Tintrup*,H.,Kirsch,J.,Nichol,M.,Kuhse,J.,Betz,H. and Sanes,J.R. (1998) Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity. Science 282:1321-1324. *co-first authors
3.Feng,G.,Hood,R.,Bernstein,M.,Keller-Peck,C.,Nguyen,Q.,Wallace,M.,Nerbonne,J.M.,Litchman,J.W. and Sanes,J.R (2000). Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP. Neuron 28:41-51.
4.Parker,M.J.,Zhao,S.,Bredt,D.S.,Sanes,J.R.,and Feng,G. (2004) PSD93 regulates synaptic stability at neuronal cholinergic synapses. J. Neurosci. 24:378-88.
5.Finn,A.J.,Feng*,G.,and Pendergast*,A.M. (2003) Postsynaptic requirement for Abl kinases in assembly of the neuromuscular junction. Nat. Neurosci. 6:717-23. *co-corresponding authors.
6.Young,P.,Nie,J.,Wang,X.,McGlade,CJ,Rich,MM,and Feng,G. (2005) Interaction of ErbB2 with LNX1 E3 ubiquitin ligase: potential role in the development of perisynaptic Schwann cells at the neuromuscular junction. Mol. Cell. Neurosci. 30:238-48.
7.Ficklin,MB.,Zhao,S.,and Feng,G. (2005) Ubiquilin-1 regulates nicotine-induced upregulation of neuronal nicotinic acetylcholine receptors. J. Biol. Chem. 280:34088-34095.
8.Wang,H.,Peca,J.,Matsusaki,M.,Matsusaki,K.,Noguchi,J.,Qiu,L.,Wang,D.,Zhang,F.,Boyden,E.,Deisseroth,K.,Kasai,H.,Hall,WC.,Feng*,G.,and Augustine*,GJ (2007) High-speed mapping of synaptic connectivity using photostimulation in Channelrhodopsin-2 transgenic mice. Proc Natl Acad Sci U S A. 104:8143-8148. *co-corresponding authors
9.Arenkiel,B.A.,Peca,J.,Davison,I.G.,Feliciano,C.,Deisseroth,K.,Augustine,G.J.,Ehlers,M.D.,and Feng,G. (2007) Light-Induced Activation of Neural Circuitry in Transgenic Mice Expressing Channelrhodopsin-2. Neuron 54:205-218.
10.Lu,Z,Je,H-S.,Young,P.,Groos,J.,Lu,B.,and Feng,G. (2007) Regulation of Synaptic Growth and Maturation by a Synapse-Associated E3 Ubiquitin Ligase at the Neuromuscular Junction. J Cell Biol. 177:1077-1089.
11.Welch,JM.,Lu,J.,Rodriguiz,RM.,Trotta,NC.,Peca,J.,Ding,J-D.,Feliciano,C.,Chen,M.,Adams,JP.,Luo,J.,Dudek,SM.,Weinberg,RJ.,Calakos,N.,Wetsel,WC.,and Feng,G. (2007) Cortico-striatal synaptic defects and OCD-like behaviors in SAPAP3 mutant mice. Nature 448:894-900.
12.Young,P.,Qiu,L.,Wang,D.,Zhao,S.,Gross,J.,and Feng,G. (2008). Single-neuron labeling with inducible cre-mediated knockout in transgenic mice. Nature Neurosci. 11:721-8.
13.Peca J,Feliciano C,Ting JT,Wang W,Wells MF,Venkatraman TY,Lascola CD,Fu Z and Feng G. (2011) Shank3 mutant mice display autistic-like behaviours and striatal dysfunction. Nature,472:437-42.
14.Halassa MM,Siegle JH,Ritt JT,Ting JT,Feng* G,Moore* CI. (2011) Selective optical drive of thalamic reticular nucleus generates thalamic bursts and cortical spindles. Nat Neurosci. 14:1118-20. *co-corresponding authors.
15.zhao,S.,Ting,JT.,Atallah HE.,Qiu,L.,Tan,J.,Gloss,B.,Augustine,GJ.,Deisseroth,K.,Luo,M.,Graybiel,AM. and Feng,G. (2011) Cell-type Specific Optogenetic Mice for Dissecting Neural Circuitry Function. Nature Methods 8:745-752.

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